The hallmark of our research is the combination of experimental physics and numerical modelling. A rich palette of analytical methods permits us to measure concentrations and isotopic ratios of many elements in environmental archives. With this information we constrain and quantify Earth System processes. We use our unique devices to measure radionuclides of several noble gases, carbon and hydrogen to determine the age of groundwater and organic matter. Our physical-biogeochemical climate models permit us to perform million-year long simulations and run large ensembles for probabilistic assessments of past and future climate change.